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GIGA research center, University of Liege in Belgiumポスドク募集

パドヴァ大学の野口雅史と申します。研究室の同僚(Dr. Stéphanie Herkenne)がベルギーで新しく研究を始めることになり、一緒に研究するポスドクを募集しております。


The Laboratory of Molecular Angiogenesis offers postdoctoral position on exosome/ extracellular vesicles research in tumoral environment.

Applications are invited for a 3-year postdoctoral position at the Laboratory of Molecular Angiogenesis for a project aiming to “Explore the extracellular vesicle landscape in pancreas cancer tumor microenvironment”. Our centre, the GIGA research center is located at the University of Liege in Belgium and offers a stimulatory intellectual and collaborative environment and state-of the art facilities.

Project description
Extracellular vesicles (EV) are small vesicles released by cells in the extracellular milieu that mediate cell-cell communication. EVs have been shown to contain RNA, DNA, lipid and proteins that define a specific repertoire of molecular cargo that are representative of their originating cells. In the context of cancer, EVs are potentially secreted by all cell types that compose in tumor microenvironment (TME). Those vesicles thus represent a new source of regulators of tumor progression.

Our lab has a 10 year-expertise in EV research in angiogenesis related diseases such as cancer. With this new project we aim to unravel the complexity of the EV landscape in pancreas cancer. Our goal is to determine which and how some specific EV released by neoplastic cells as well as from stromal cells impact on tumorigenicity of pancreas cancer. To achieve this goal, we will first characterize the population of EV in a murine model of pancreatic ductal adenocarcinoma (PDAC). Based on their surface markers we will select specific EV populations and determine their role in pancreas cancer pathogenicity. Then, longitudinal studies will be performed to determine the evolution of the EV landscape during PDAC initiation and progression

Profiles :
The candidate should have a Ph.D. in the field of biological, biomedical, medical sciences or equivalent
She/he should have advanced experience in tumor and cellular biology: in vivo experience with mice, knowledge of basic immunology tools
Expertise in Molecular biology, RNA biology and exosome are an important asset.
She/he must have shown research abilities and capabilities to perform collaborative project within a team, and possess good written and verbal communication skills in English. Ability to work independently, good communication and enthusiastic personality are expected.
The candidate must be non-Belgian citizens and should not have lived and/or worked in Belgium for more than 24 months during the past 3 years.

For application, send C.V., contact information for two references, and a brief motivation letter including a summary of research experience to:
Ingrid Struman i.struman@uliege.be


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