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University of North Carolina at Chapel Hill Postdoctral Position

Postdoctoral Training Immunology and Autoimmune Disease

A postdoc position is immediately available in the Vilen lab at the
University of North Carolina at Chapel Hill.

Our lab focuses on the mechanisms underlying immune dysfunction in autoimmune disease. We identified that in systemic lupus erythematosus (SLE), defects in lysosome acidification reduce degradation of IgG-immune complexes that enter myeloid cells by phagocytosis. This defect leads to multiple pathologies associated with murine SLE. Our recently funded NIH/DOD grants propose translational studies to assess whether lysosome dysfunction underlies human SLE, and studies to assess whether restoring lysosome function prevents onset or attenuates progression of disease in mice. Other goals seek to define the molecular and genetic events that drive lysosome dysfunction. Thus, projects are available to study murine or human aspects of lupus. Detailed research information is available on our websites: https://www.vilenlab.com/ and https://www.med.unc.edu/microimm/directory/barbara-vilen-phd/.

Successful candidates require a background in immunology, experiences in murine models or human translational research and good English speaking and writing skills. A sound track-record of publishing, and strong internal motivation are essential. Experiences in flow cytometry/microscopy (multicolor, multiple cell types), animal models (injection, bleeding, organ processing) are preferred. Salary is based on years of quality experience. Time period is variable, but funding is in-place for 4 years.

UNC-Chapel Hill is situated between the Blue Ridge Mountains and the NC Beaches, close to Durham, Raleigh, and Research Triangle Park. It has an excellent, collaborative research environment.

Please send CV including contact information for three references,
and cover letter (optional) to:

Barbara Vilen, Ph.D. (barb_vilen@med.unc.edu)
Department of Microbiology & Immunology, 6110 Marsico Hall
University of North Carolina at Chapel Hill


Vilen labではポスドク一名を急ぎ募集します。


応募先:Barbara Vilen, Ph.D. (barb_vilen@med.unc.edu)

ノースカロライナ大学チャペルヒル校はBlue Ridge Mountains と NC Beaches の間に位置し、Durham, Raleighとリサーチトライアングルパークを形成しています。デューク大学やノースカロライナ州立大学、National Institute of Environmental Health Sciences (NIEHS)との素晴らしいコラボレーションが可能なエリアです。


Barbara Vilen, Ph.D. (barb_vilen@med.unc.edu)
Department of Microbiology & Immunology, 6110 Marsico Hall
University of North Carolina at Chapel Hill

Posted by Barbara Vilen(barb_vilen@med.unc.edu)

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